Neoprene Gasket Neoprene gasket, also known as neoprene polychloroprene, is an extremely versatile synthetic rubber with more than 75 years of proven performance. In the automotive world, neoprene gasket is used for many under-the-hood and underbody parts that require a reasonably priced, mid-performance polymer with a good all-around balance of performance properties Neoprene Gasket is used for: ...