Low shearing force, rapid solution circulation , shorter mixing time, and ability of linear scale up. Shanghai RITAI introduces a new generation of microcarrier Cell Culture Bioreactors. We adopt centrifugal lifting type Agitator, which has features of low shearing force, rapid solution circulation , shorter mixing time, and ability of linear scale up. And we adopt new type of aeration tube, which has features of foam free deep aeration, oxygen Transfer Rate (Kla between 4-8) satisfy.. Moreover, we also adopt unique decanting column, which has features of Simple structure, stable and reliable, Perfusion rate higher than 5 times of the working volume/per day, a self cleaning function and of features of liquid level being automatically controlledApplicationIt suit for mammalian animal cell culture. it is also available for suspension culture , anchorage independent and anchorage dependent cell line. Continuous perfusion is applicable, it can increase cell density, improve the health pattern of cell, and greatly increase cell product.
| Model | CELLIPOWER08 SYSTEM | ||||||
| Working volume | 5L,10L,15L | ||||||
| Filling volume | 65-80% | ||||||
| Material | Special type of magnetic silicone glass , which can resist temp. and pressure. Wetted parts are SS316L, and others is SS304. | ||||||
| Stainless steel part finish | inside surface is 0.28-0.6μm by mechanical polishing, ( passivation or electropolish are optional) outside surface is 0.4-0.8μm by satin finish. | ||||||
| Pressure | ATM (atmospheric pressure) | ||||||
| Agitation | 11. Fermentor use servo motor 2.top mechanical agitator , single mechanical seal 3.speed range:50-200rpm 4. Centrifugal lifting type agitator | ||||||
| Equips of vessel | 1.using alcohol flame inoculation 2.electrical heater 3.PH,DO, temp. sensor foam and level probe port, etc. | ||||||
| construction | bench-top One fermentor vessel with one control system (simens PLC and HMI) | ||||||
| Operating panel | Chinese and English version | ||||||
| Main components and controls of system | |||||||
| PH | 1.On-line check and measure, and digitization fully automatic control; 2.PH, CO2 and base gang control. Mass flow meter automatically adjusting CO2, peristaltic pump automatically adjusting base. 3.Control range 2-12pH, measure precision±0.01 pH, control precision±0.1 pH; 4. It has auto alarm function. 5.pH sensor and signal transmission line, mettler Toledo | ||||||
| DO | 1.On-line check and measure; digital display. 2.Range 0-200%, precision ±1%; 3.It has auto alarm function; 4.DO sensor and signal transmission line, mettler Toledo | ||||||
| Feed controlperfusion | 1.Automatically control and automatically alarm; 2.peristaltic pump automatically feeding and perfusion | ||||||
| Temp. control | 1.PID fully digitization signal processing, digitization control settings 2.Measure range 0-150°C, control range 15-45°C,control precision±0.2°C 3.Pt 100Ωtemp. Sensor 4.system with electrical heater to control the temp inside vessel | ||||||
| Rotate speed | 1.Automatically control , with auto alarm function 2.servo frequency converter to adjust the speed. | ||||||
| Air flow | Automatically adjusting with massflow meter | ||||||
| sterilization | Should sent to autoclave for sterilization | ||||||
| Control | Siemens PLC, and Siemens 10.4” LCD touch screen(HMI) and RITAI program | ||||||
| PC | 1.PC with kingview software for recording function (optional) 2.PC with simens remote control and kingview recording function (optional) 3.printer (optional) | ||||||
CELL CULTURE BIOREACTOR WITH CENTRIGUAL LIFTER
